About
Dr. Yazhen Zhu is currently an Assistant Professor and Research Pathologist at the David Geffen School of Medicine at UCLA. She received her MD degree from Wuhan University in 2005 and her PhD degree in Pathology from Fudan University in 2010. In 2012, she completed her residency training in the Pathology Department of Guangdong Provincial Hospital of TCM (China) where she served as an attending pathologist for the next five years. Her clinical practice covered surgical pathology in gastrointestinal cancer, thyroid cancer, and breast cancer. In 2013-2017, she also served as the founding Director of the Molecular Pathology Laboratory of the Pathology Department, where she developed and validated a collection of laboratory-developed tests (LDTs) for detecting oncogenic mutations for targeted cancer therapy. Dr. Zhu’s experience in molecular pathology equipped her with a unique strength for identifying unmet clinical needs in translational research for cancer diagnostics. In 2015, Dr. Zhu joined UCLA Pharmacology as a visiting assistant project scientist. In 2020, she became a faculty member in the Crump Institute for Molecular Imaging and the Department of Molecular and Medical Pharmacology.
Education and Degree(s)
- M.D
- Ph.D
Publications
- B7-H3-liquid biopsy for the characterization and monitoring of the dynamic biology of prostate cancer. Drug Resist Updat. 2025 Mar; 79:101207.Ju Y, Watson J, Wang JJ, Yen YT, Gevorkian L, Chen Z, Tu KH, Salumbides B, Phung A, Zhao C, Kim H, Ji YR, Zhang RY, Lee J, Gong J, Scher K, You S, Chen JF, Tseng HR, Zhu Y, Posadas EM. PMID: 39914189.
- Author Correction: Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer. Nat Commun. 2024 May 01; 15(1):3693.Stackpole ML, Zeng W, Li S, Liu CC, Zhou Y, He S, Yeh A, Wang Z, Sun F, Li Q, Yuan Z, Yildirim A, Chen PJ, Winograd P, Tran B, Lee YT, Li PS, Noor Z, Yokomizo M, Ahuja P, Zhu Y, Tseng HR, Tomlinson JS, Garon E, French S, Magyar CE, Dry S, Lajonchere C, Geschwind D, Choi G, Saab S, Alber F, Wong WH, Dubinett SM, Aberle DR, Agopian V, Han SB, Ni X, Li W, Zhou XJ. PMID: 38693151; PMCID: PMC11063198.
- Placenta accreta spectrum disorder at single-cell resolution: a loss of boundary limits in the decidua and endothelium. Am J Obstet Gynecol. 2024 04; 230(4):443.e1-443.e18.Afshar Y, Yin O, Jeong A, Martinez G, Kim J, Ma F, Jang C, Tabatabaei S, You S, Tseng HR, Zhu Y, Krakow D. PMID: 38296740.
- Exosomes from Von Hippel-Lindau-Null Cancer Cells Promote Metastasis in Renal Cell Carcinoma. Int J Mol Sci. 2023 Dec 09; 24(24).Flora K, Ishihara M, Zhang Z, Bowen ES, Wu A, Ayoub T, Huang J, Cano-Ruiz C, Jackson M, Reghu K, Ayoub Y, Zhu Y, Tseng HR, Zhou ZH, Hu J, Wu L. PMID: 38139136; PMCID: PMC10743428.
- Hierarchical integration of DNA nanostructures and NanoGold onto a microchip facilitates covalent chemistry-mediated purification of circulating tumor cells in head and neck squamous cell carcinoma. Nano Today. 2023 Apr; 49.Sun N, Zhang C, Wang J, Yue X, Kim HY, Zhang RY, Liu H, Widjaja J, Tang H, Zhang TX, Ye J, Qian A, Liu C, Wu A, Wang K, Johanis M, Yang P, Liu H, Meng M, Liang L, Pei R, Chai-Ho W, Zhu Y, Tseng HR. PMID: 38037608; PMCID: PMC10688595.
HCC EV ECG score: An extracellular vesicle-based protein assay for detection of early-stage hepatocellular carcinoma. Hepatology. 2023 03 01; 77(3):774-788.Sun N, Zhang C, Lee YT, Tran BV, Wang J, Kim H, Lee J, Zhang RY, Wang JJ, Hu J, Zhang Z, Alsudaney MS, Hou KC, Tang H, Zhang TX, Liang IY, Zhou Z, Chen M, Yeh AH, Li W, Zhou XJ, Chang HR, Han SB, Sadeghi S, Finn RS, Saab S, Busuttil RW, Noureddin M, Ayoub WS, Kuo A, Sundaram V, Al-Ghaieb B, Palomique J, Kosari K, Kim IK, Todo T, Nissen NN, Tomasi ML, You S, Posadas EM, Wu JX, Wadehra M, Sim MS, Li Y, Wang HL, French SW, Lu SC, Wu L, Pei R, Liang L, Yang JD, Agopian VG, Tseng HR, Zhu Y. PMID: 35908246; PMCID: PMC9887095.