Shili Xu
Assistant Professor
About
Dr. Shili Xu received a B.S. in Biological Sciences and a B.S. in Economics from Peking University. He received a Ph.D. from the University of Southern California where he studied small-molecule drug design and discovery. He then studied cell metabolism, molecular imaging, and synthetic lethality for cancer therapy in a variety of small animal models as a post-doctoral fellow at the University of California Los Angeles (UCLA). He is currently Director of Preclinical Imaging in the Crump Institute for Molecular Imaging, and Assistant Professor of Molecular and Medical Pharmacology at UCLA.
Education and Degree(s)
- Ph.D
Publications
- John S, Calmettes G, Xu S, Ribalet B. Real-time resolution studies of the regulation of lactate production by hexokinases binding to mitochondria in single cells.. PloS one, 2024.
- Narayanam MK, Tsang JE, Xu S, Nathanson DA, Murphy JM. 18F-Labeled brain-penetrant EGFR tyrosine kinase inhibitors for PET imaging of glioblastoma.. Chemical science, 2023.
- Bailleul J, Ruan Y, Abdulrahman L, Scott AJ, Yazal T, Sung D, Park K, Hoang H, Nathaniel J, Chu FI, Palomera D, Sehgal A, Tsang JE, Nathanson DA, Xu S, Park JO, Ten Hoeve J, Bhat K, Qi N, Kornblum HI, Schaue D, McBride WH, Lyssiotis CA, Wahl DR, Vlashi E. M2 isoform of pyruvate kinase rewires glucose metabolism during radiation therapy to promote an antioxidant response and glioblastoma radioresistance.. Neuro-oncology, 2023.
- John S, Calmettes G, Xu S, Ribalet B. Real-time resolution studies of the regulation of pyruvate-dependent lactate metabolism by hexokinases in single cells.. PloS one, 2023.
- Han M, Bushong EA, Segawa M, Tiard A, Wong A, Brady MR, Momcilovic M, Wolf DM, Zhang R, Petcherski A, Madany M, Xu S, Lee JT, Poyurovsky MV, Olszewski K, Holloway T, Gomez A, John MS, Dubinett SM, Koehler CM, Shirihai OS, Stiles L, Lisberg A, Soatto S, Sadeghi S, Ellisman MH, Shackelford DB. Spatial mapping of mitochondrial networks and bioenergetics in lung cancer.. Nature, 2023.
- Gelb MB, Messina KMM, Vinciguerra D, Ko JH, Collins J, Tamboline M, Xu S, Ibarrondo FJ, Maynard HD. Poly(trehalose methacrylate) as an Excipient for Insulin Stabilization: Mechanism and Safety.. ACS applied materials & interfaces, 2022.
Honors and Awards
- The Alavi-Mandell Award, Society of Nuclear Medicine and Molecular Imaging, 2020.
- The Hirshberg Foundation Seed Grant Award, The Hirshberg Foundation, 2018.
- Best Postdoctoral Research Presentation Award, UCLA, 2017.
- The Horizon Award, US Department of Defense, 2016.
- Best Research Poster Presentation Award, UCLA, 2015.
- GPSAW Award for Best Graduate Research, University of Southern California, 2013.
- Outstanding Research Assistant Award, University of Southern California, 2013.
- Phi Kappa Phi Student Recognition Award, University of Southern California, 2013.
- The 1st Prize in Annual Graduate STEM Research Competition, University of Southern California, 2013.
- The 1st Prize in Research Poster Presentation, University of Southern California, 2012.
- Outstanding Teaching Assistant Award, University of Southern California, 2009.
- President’s Undergraduate Research Fellowship, Peking University, 2006.
- Jia-Li Scholarship, Peking University, 2005.
- Guang-Hua Scholarship, Peking University, 2004.